In what passes for an ordinary day in a psych ward, Dr. Zoe Goldman is stumped when a highly unusual case arrives. A young African American girl, found wandering the streets of Buffalo in a catatonic state, is brought in by police. No one has come forward to claim her, and all leads have been exhausted, so Zoe's treatment is the last hope to discover the girl's identity.
When drugs prove ineffective and medical science seems to be failing, Zoe takes matters into her own hands to track down Jane Doe's family and piece together their checkered history. As she unearths their secrets, she finds that monsters hide where they are least expected. And now she must solve the mystery before it is too late. Because someone wants to make sure this young girl never remembers.